The 5-Phosphatase SHIP2 Promotes Neutrophil Chemotaxis and Recruitment
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چکیده
منابع مشابه
Adenosine promotes neutrophil chemotaxis
We have previously (1-4) demonstrated that adenosine, by engaging specific receptors on the surface of neutrophils, inhibits generation of toxic oxygen metabolites by activated neutrophils and prevents these activated neutrophils from injuring endothelial cells. We now report the surprising observation that engagement of these same neutrophil adenosine receptors promotes chemotaxis to C5 fragme...
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Using a modified Boyden technique, the ability of normal human neutrophils to migrate in response to chemotactic stimulation was evaluated during exposure in vitro to halothane and thiopentone. No abnormality in neutrophil chemotaxis could be demonstrated with either agent at concentrations used clinically. The anaesthetics also did not effect serum complement, which was used as the chemotactic...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.671756